Very Rare Cancer Consortium Disease Spotlight & Research Roundtable

Please join us for the Very Rare Cancer Consortium Tumor Board Meeting. This new initiative aims to bring cancer researchers across New York to the table to discuss compelling rare cancer cases presented by physicians and scientists from the New York Genome Center’s partner institutions.

DESMOPLASTIC SMALL ROUND CELL TUMOR (DSRCT)

Disease Spotlight & Research Roundtable

Please note registration is required.

Desmoplastic small round cell tumor (DSRCT) is a rare and aggressive cancer occurring predominantly in adolescents and young adults. Although DSRCT’s characteristic translocation between the EWSR1 and WT1 genes has been well described, the disease overall remains poorly understood and overall survival for patients with DSRCT remains unacceptably low. Given the rarity of the disease, no randomized trials have been performed and pre-clinical tools in which to study the disease remain limited, making collaborative efforts essential. We will hear from experts about the current understanding of DSRCT, review the many areas in which this understanding could be deepened, and discuss potential collaborations through the VRCC.

Any questions on this event, contact events@nygenome.org.

Speakers

• 

  Emily Slotkin, MD

  Pediatric Sarcoma Service, MSK KIDS
  Memorial Sloan Kettering Cancer Center

  "Introduction to the Disease"

• 

  Marc Ladanyi, MD

  Attending Pathologist and Chief, Molecular Diagnostics Service
  Member, Human Oncology & Pathogenesis Program
  Memorial Sloan Kettering Cancer Center
  Affiliate Member
  New York Genome Center

  "Genomic and Molecular Landscape"

• 

  Alex Kentsis, MD, PhD

  Director, Tow Center
  for Developmental Oncology,
  Sloan Kettering Institute and Department of Pediatrics, MSK Kids
  Memorial Sloan Kettering Cancer Center
  Departments of Pediatrics, Pharmacology, and Physiology & Biophysics,
  Weill Medical College of Cornell University

  "Causes and Function of Chromosomal Translocations in DSRCT"

• 

  Andrea Califano, PhD

  Clyde and Helen Wu Professor of Chemical and Systems Biology
  Founding Chair, Department of Systems Biology
  Director, JP Sulzberger Columbia Genome Center
  Associate Director for Bioinformatics,
  Herbert Irving Comprehensive Cancer Center
  Columbia University Irving Medical Center
  Affiliate Member
  New York Genome Center

  "Transcriptomics and Unique Bioinformation Approaches in DSRCT"

• 

  Prabhjot S. Mundi, MD

  Department of Medicine
  Division of Hematology/Oncology
  Columbia University Irving Medical Center

• 

  Emily Slotkin, MD

  Pediatric Sarcoma Service, MSK KIDS
  Memorial Sloan Kettering Cancer Center

  "Review of Investigational Therapeutic Approaches"

• 

  Marc Ladanyi, MD

  Attending Pathologist
  and Chief, Molecular Diagnostics Service
  Member, Human Oncology & Pathogenesis Program
  Memorial Sloan Kettering Cancer Center
  Affiliate Member
  New York Genome Center

• 

  Madelyn Espinosa-Cotton, PhD

  Research Fellow
  The Nai-Kong Cheung Lab
  Memorial Sloan Kettering Cancer Center

• 

  Lauren Banks, MD, PhD
  Hematology/Oncology Fellow
  Memorial Sloan Kettering Cancer Center

• 

  Joseph A. Ludwig, MD

  Associate Professor
  Department of Sarcoma Medical Oncology,
  Division of Cancer Medicine
  University of Texas MD Anderson Cancer Center